- Tina Hesman Saey- Tina Hesman Saey is a senior writer covering molecular biology for Science News magazine. She has a Ph.D. in molecular genetics and a masters degree in science journalism. 
- Andrew Sagar- Andrew Sagar has spent over 20 years in the film/TV industry as a VFX supervisor and producer. He has spent time both on set and in post. 
- Jenn Sapp- Jenn Sapp is a director for the Atlanta Film Society, producer of the annual Atlanta Film Festival, and serves on the advisory board of the Morehouse Human Rights Film Festival. 
- Tony Sarrecchia- Tony Sarrecchia is a writer and narrator who creates audio dramas, including the award winning Harry Strange Radio Drama and Everything Evolves. 
- Daniel Schinhofen- Daniel Schinhofen has published over 60 books since 2016, receiving name recognition in the LitRPG and GameLit community. He has published in multiple other genres as well. 
- Anne Schlea- Anne Schlea writes two series: The Retribution Universe and The Fallen. She enjoys blending true history into urban fantasy to create a dynamic world for her readers to step into. 
- Jen Lil' Bit Schleusner- Jen Schleusner, aka Lil Bit, has been a Dragon Con staple since 2010, a co-host and producer of the Dragon Con Report, ESO Network board member, and digital media creator. 
- Stephen Seitz- Stephen Seitz is a craftsman, DJ, and tournament organizer at gaming panels for Dragon Con. He built giant, wooden Nintendo Game Boy Advance consoles, ready for gaming! 
- Bruce Sentar- Bruce Sentar writes romantic fantasy for men in the LitRPG, fantasy, and urban fantasy spaces. He has numerous accolades, 40 published books, and over 100k reviews on Amazon. 
- Ingrid Seymour- Ingrid Seymour is a USA Today bestselling author of 57 novels, specializing in fantasy romance, urban fantasy, and paranormal romance. Her hit novel A Prince So Cruel gained viral success. 
- Nash Sheard- As the managing director for advocacy, Nash works to ensure the Electronic Frontier Foundation's work protecting your rights in the digital world is impactful, collaborative, and innovative. 
- Isaac Sheff- Dr. Isaac Sheff is a computer scientist working on distributed systems research, with a background in security, programming languages, and blockchains. 
- Channing Scott Sherman- Channing Sherman, co-host of the Dragon Con Report podcast, is a digital media creator, journalist, and podcaster. He co-founded the Black Geeks of Dragon Con. 
- David Sherrer- David Sherrer is a lifelong gamer and story teller, and is the marketing director of Chenoweth Press and lead game designer of Chenoweth Games. 
- Lydia Sherrer- Award winning and USA Today bestselling author Lydia Sherrer is best known for her Love, Lies, and Hocus Pocus universe novels full of snarky humor and a talking cat. 
- Aron Siegel- Aron Siegel is a producer and sound mixer whose work includes The Unwanted, Implanted, Thor: Ragnarok,  DC's Black Lightning, Walking Dead, and Vampire Diaries. 
- R Alan Siler- R. Alan Siler is an editor, publisher, musician, podcaster, filmmaker, owner of kOZMIC Creative, and the author of four books about Doctor Who and a children's book Lucy Can't Dance. 
- Tamsin L. Silver- Tamsin Silver is a New Mexico based author who writes historical fantasy and urban fantasy. She is also the creator/writer/director of the web series, Skye of the Damned. 
- Melissa Simpson- Melissa Simpson is the executive director of the nonprofit Film Impact Georgia, the education director at the Atlanta Film Society, and produces independent projects. 
- Allen Slonaker- Allen Slonaker joined CPRI in 2007 and currently serves on CPRI's Board of Directors. Slonaker has a Bachelor of Science degree in Criminal Justice from Virginia Commonwealth University. 
- Fr. Bryan Small- Every D&D group needs a cleric, no? A priest for over 15 years, Fr. Bryan Small loves to share in the fandoms with his fellow nerds. 
- Wayland Smith- Wayland Smith has been published in most genres. His novels include In My Brother's Name, a terrorist thriller, and the Wildside series about superhuman mercenaries. 
- Charles St. John Smith III- Charles St. John Smith III is a producer on the Emmy Award winning Albie's Elevator. He directed Zeroes and produced Neighbor, Mayor Cupcake, Lebanon, PA, and more. 
- Fruity Snacks- Fruity Snacks is an instructional designer who owns the Eorzean Aquarium and Eorzean Museum Network, and has a YouTube channel for teaching how to catch fish in Final Fantasy XIV. 
- Arley Sorg- Arley Sorg is an associate agent at kt literary, asco-editor-in-chief at Fantasy Magazine, senior editor at Locus, and associate editor at Lightspeed & Nightmare. 
- Sarah J. Sover- Sarah J. Sover is the author of the urban fantasy Fractured Fae series (Fairy Godmurder, Faed to Black) and the comedic fantasy Double-Crossing the Bridge, from Falstaff Books. 
-  Spat- Spat Oktan of SpatCave Studios is an FX makeup artist, costume/prop maker, and author known for his MOBCon book series, his crazy costumes, and makeup effects. 
- John J Spearman- John Spearman is the award winning author of Mercenary Navy, Jonah Halberd, Perseverance Andrews, and Sandy Pike series of science fiction novels, and the FitzDuncan fantasy books. 
- Teresa Spinelli- Teresa Spinelli is a mission director of the Cygnus spacecraft, resupplying the International Space Station. She is the youngest and first woman certified to lead the Cygnus Flight Operations team. 
- Kevin Stallard- Kevin Stallard has been in the IT security business for 30+ years, but has always been a video gamer.  Recently working at Activision/Blizzard, Stallard is working on a new title. 
- Darcy Staniforth- Darcy Staniforth is a scholar, writer, performer, and paranormal investigator. Research areas include race and ethnicity, gender and sexuality, ideals and institutions, and death, dying, and grief in American culture. 
- Jessica Sarah Schonhut Stasik- Dr. Jess is an autistic astrophysicist specializing in galactic archaeology, CEO of The Neuroverse Initiative, and communications director for the Frist Center for Autism and Innovation. 
- Judy Stephens- Judy Stephens is an author, producer, host, photographer, and cosplayer who has written two books for Marvel: Cosplay the Marvel Way and Super Visible: the Story of the Women of Marvel. 
- Dot R Steverson- Dot is a podcaster, producer, digital storyteller, and game designer based in Atlanta. Currently, she serves as the marketing director for Kobold Press. 
- Brandon H. Strauss- Brandon Strauss is a forensic entomologist and the resident grossologist of the Science Track. You will often find them grossing out their fellow panelists to the audience's amusement. 
- Ian Randal Strock- Ian Randal Strock is the award winning author and publisher responsible for Release the Virgins and Jewish Futures. He previously edited for Analog, Asimov's, Science Fiction Chronicle, and Baen Books. 
-  Sunhi- Black Girls Anime is a platform celebrating Black girls who love anime, offering news, reviews, and entertainment that highlights their unique experiences. 
-  Sunlight of Astora- 11 time award winning, Johnny Goodwill "Sunlight of Astora" creates costumes based off of dark fantasy and horror video games, along with props and effects for tv and film. 
- Jordan Diana Swartz- Jordan Swartz is a crime scene investigator in Los Angeles County, California. She has processed over 300 crime scenes and has lent her expertise to several productions as a consultant.